Research and Innovation of Production Technology for Low Allergenic Peanut Products

Authors

  • Chunpeng Zhang Yantai Rongke Biotechnology Co., Ltd., Yantai, Shandong, China Author

Abstract

Hypoallergenic peanut products are developed to address the health risks and nutritional challenges associated with peanut allergy, one of the most common food allergies worldwide. This study delves into the application of various technologies in reducing peanut allergenicity, including chemical, physical, enzymatic, and biological techniques. Specifically, chemical methods reduce IgE binding ability by modifying protein structures; physical methods such as high-temperature treatment and high-pressure treatment can significantly reduce the activity of allergenic proteins while maintaining nutrition; enzyme treatment utilizes enzymatic decomposition or cross-linking to alter the structure of allergens, significantly reducing their allergenicity. In addition, biotechnology methods such as microbial fermentation further enhance the biological activity of peanut protein while reducing the levels of major allergens such as Ara h1 and Ara h2. The research results indicate that by optimizing processing, peanut protein can become safer and more suitable for a wider consumer group, which is of great significance for improving food labeling practices. With the increase of sugar concentration, pressure, and fermentation time, the content of allergens (Ara h1 and Ara h2) in peanuts significantly decreases. Under the premise of controlling pressure, high-pressure treatment can still reduce allergen content to a certain extent while retaining most of the nutritional components.

References

[1] Boukid F. Peanut protein–an underutilised by-product with great potential: a review[J]. International journal of food science & technology, 2022, 57(9): 5585-5591.

[2] Krejner-Bienias A, Grzela K, Kulus M, et al. Peanut contamination in food products: a real danger for allergic people?[J]. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 2023, 40(5): 625-629.

[3] Geng Q, Zhang Y, Song M, et al. Allergenicity of peanut allergens and its dependence on the structure[J]. Comprehensive Reviews in Food Science and Food Safety, 2023, 22(2): 1058-1081.

[4] Turner P J, Patel N, Ballmer-Weber B K, et al. Peanut can be used as a reference allergen for hazard characterization in food allergen risk management: a rapid evidence assessment and meta-analysis[J]. The Journal of Allergy and Clinical Immunology: In Practice, 2022, 10(1): 59-70.

[5] Yang S, Peng Z, Hardie W J, et al. Screening of probiotic Lactobacillus to reduce peanut allergy and with potential anti‐allergic activity[J]. Journal of the Science of Food and Agriculture, 2024, 104(4): 2006-2014.

[6] Roberts G, Bahnson H T, Du Toit G, et al. Defining the window of opportunity and target populations to prevent peanut allergy[J]. Journal of Allergy and Clinical Immunology, 2023, 151(5): 1329-1336.

[7] Hariharan S, Patti A, Arora A. Functional proteins from biovalorization of peanut meal: advances in process technology and applications[J]. Plant Foods for Human Nutrition, 2023, 78(1): 13-24.

[8] Abu Risha M, Rick E M, Plum M, et al. Legume allergens pea, chickpea, lentil, lupine and beyond[J]. Current Allergy and Asthma Reports, 2024, 24(9): 527-548.

[9] La Vieille S, Hourihane J O B, Baumert J L. Precautionary allergen labeling: what advice is available for health care professionals, allergists, and allergic consumers?[J]. The Journal of Allergy and Clinical Immunology: In Practice, 2023, 11(4): 977-985.

[10] Miller T A, Koppelman S J, Bird J A, et al. Peanut cross-contamination in randomly selected baked goods[J]. Annals of Allergy, Asthma & Immunology, 2022, 128(4): 439-442.

[11] Chang X, Zhou X, Tang Y, et al. Effect of processing on the structure and allergenicity of peanut allergen Ara h 2 roasted in a matrix[J]. Journal of Agricultural and Food Chemistry, 2022, 70(2): 626-633.

[12] Kim E H, Keet C A, Virkud Y V, et al. Open-label study of the efficacy, safety, and durability of peanut sublingual immunotherapy in peanut-allergic children[J]. Journal of Allergy and Clinical Immunology, 2023, 151(6): 1558-1565. e6.

[13] Eischeid A C. Optimised multiplex droplet digital PCR is more precise, but not more sensitive, than real-time PCR for the detection of allergenic peanut[J]. Food Additives & Contaminants: Part A, 2022, 39(11): 1797-1805.

[14] Hsu F C, Lin W T, Hsieh K C, et al. Mitigating the allergenicity of peanut allergen Ara h 1 by cold atmospheric pressure argon plasma jet[J]. Journal of the Science of Food and Agriculture, 2023, 103(6): 3017-3027.

[15] Durham S R, Shamji M H. Allergen immunotherapy: past, present and future[J]. Nature Reviews Immunology, 2023, 23(5): 317-328.

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Published

2024-12-03